The Role and Significance of Biomarkers in the Diagnosis of Dental Disease: A Depth Review Study, Challenges, Limitations and Future Directions

Ibtihal Faisal S Alanazi, Karimah Abdullah S Al Balawi, Ahlam Hameed H Albalawi, Mashael Fahad A Albalawi, Safa Mohammed Ali Albalawi, Hessah Hameed H Albalawi, Najah Hassan Kaabi, Mofareh Mohammed A Alamri,
Ahmed Mohammed Saeed Alzahrani*, Haifa Anber Altimawi, Nujud Ibrahim H Alquzi, Raniyah Dhahi A Kaabi, Sarah Suwailem E Alatawi, Reem Saleh Alhwaiti, Norah Alhumaidi M Alanazi

Abstract

This research on the biomarkers in periodontal diseases emphasizes the use of salivary and gingival crevicular fluid biomarkers, like MMP-8, IL-1β, and RANKL, as basic tools for the early diagnosis, follow-up assessment of the progression of disease, and response to treatment. The application of non-invasive diagnostic approaches, like salivary diagnostics, was also recommended for enhanced accuracy and access. The biological mechanisms of the biomarkers were seen as the backbone of knowledge through which an individualized approach toward the management of diseases like periodontal diseases can be created.

How to Cite

Ibtihal Faisal S Alanazi, Karimah Abdullah S Al Balawi, Ahlam Hameed H Albalawi, Mashael Fahad A Albalawi, Safa Mohammed Ali Albalawi, Hessah Hameed H Albalawi, Najah Hassan Kaabi, Mofareh Mohammed A Alamri, & Ahmed Mohammed Saeed Alzahrani*, Haifa Anber Altimawi, Nujud Ibrahim H Alquzi, Raniyah Dhahi A Kaabi, Sarah Suwailem E Alatawi, Reem Saleh Alhwaiti, Norah Alhumaidi M Alanazi. (2024). The Role and Significance of Biomarkers in the Diagnosis of Dental Disease: A Depth Review Study, Challenges, Limitations and Future Directions. EVOLUTIONARY STUDIES IN IMAGINATIVE CULTURE, 1–25. https://doi.org/10.70082/esiculture.vi.2641