Hind Gale Naji Almutairi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Essa Musallam Mualla Alruwaythi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Majdi Abdullah Alahmadi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Reem Salem Alsaedi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Nadia Salem Albalawi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Wedyan Eid Shaher Alshoun
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Amin Marzouq Alharbi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Abdullalh Hamza Ali Alshelali
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Tamazoor Bashed Omar Alfooti
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Faisal Saleem Alfraidy
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Mohammad Abdullah Hallal Alharbi
Madinah Health Cluster, Ministry of Health, Saeed bin Al-Aas, Al Jamiah, Madinah 42351, Saudi Arabia
Mohammad Haleel A Alharbi
Jeddah Second Health Cluster, Alamal Plaza Hail Street PO Box 6659, Jeddah, Saudi Arabia
Mosaad Sad Al-Sadi
King Fahad hospital Madinah, Al Jamiah-3177, Madinah-42351, Saudi Arabia
Yousef Nafea Ali Alfuhaydi
Ohud General Hospital, As Salam, 7118, Medina 42354, Saudi Arabia
Eman Waslallah Alalawi
King Salman Medical City in Madinah, Mahzur, Madinah 42316, Saudi Arabia
Abstract
Pharmacogenomics, the science of studying how genetic variation affects drug response, provides the backbone for personalized medicine. It improves therapeutic outcomes, reduces ADRs, and tailors drugs to individual patients by integrating genetics with pharmacology. This paper discusses the application of pharmacogenomics in clinical and microbial settings and indicates the prospect of it revolutionizing health care through personalized treatment approaches. Pharmacogenomics has been touted to help improve drug safety, at least in fields like oncology, psychiatry, and infectious diseases, all of which make use of genetic biomarkers in medicine choice and dosing. Many challenges have marred widespread adoption, among them lacking provider education, high test costs, ethical issues, and unequal access. It shall analyze some of the gaps that this paper seeks to close concerning clinical decision support systems and guidelines, including those that the Clinical Pharmacogenetics Implementation Consortium has proposed. Further, it shall cover the application of pharmacogenomics in fighting antimicrobial resistance and how it may benefit therapy development. As healthcare shifts toward precision medicine, pharmacogenomics might become transformative, but that success will depend on the reduction of barriers through education, research, and policy changes.