Integrating Pharmacogenomics into Clinical and Microbial Practice: A Pathway for Personalized Healthcare

Hind Gale Naji Almutairi
Essa Musallam Mualla Alruwaythi
Majdi Abdullah Alahmadi
Reem Salem Alsaedi
Nadia Salem Albalawi
Wedyan Eid Shaher Alshoun
Amin Marzouq Alharbi
Abdullalh Hamza Ali Alshelali
Tamazoor Bashed Omar Alfooti
Faisal Saleem Alfraidy
Mohammad Abdullah Hallal Alharbi
Mohammad Haleel A Alharbi
Mosaad Sad Al-Sadi
Yousef Nafea Ali Alfuhaydi
Eman Waslallah Alalawi

Abstract

Pharmacogenomics, the science of studying how genetic variation affects drug response, provides the backbone for personalized medicine. It improves therapeutic outcomes, reduces ADRs, and tailors drugs to individual patients by integrating genetics with pharmacology. This paper discusses the application of pharmacogenomics in clinical and microbial settings and indicates the prospect of it revolutionizing health care through personalized treatment approaches. Pharmacogenomics has been touted to help improve drug safety, at least in fields like oncology, psychiatry, and infectious diseases, all of which make use of genetic biomarkers in medicine choice and dosing. Many challenges have marred widespread adoption, among them lacking provider education, high test costs, ethical issues, and unequal access. It shall analyze some of the gaps that this paper seeks to close concerning clinical decision support systems and guidelines, including those that the Clinical Pharmacogenetics Implementation Consortium has proposed. Further, it shall cover the application of pharmacogenomics in fighting antimicrobial resistance and how it may benefit therapy development. As healthcare shifts toward precision medicine, pharmacogenomics might become transformative, but that success will depend on the reduction of barriers through education, research, and policy changes.

How to Cite

Hind Gale Naji Almutairi, Essa Musallam Mualla Alruwaythi, Majdi Abdullah Alahmadi, Reem Salem Alsaedi, Nadia Salem Albalawi, Wedyan Eid Shaher Alshoun, … Eman Waslallah Alalawi. (2025). Integrating Pharmacogenomics into Clinical and Microbial Practice: A Pathway for Personalized Healthcare . EVOLUTIONARY STUDIES IN IMAGINATIVE CULTURE, 512–533. https://doi.org/10.70082/esiculture.vi.2807